Sponge holobiont-associated RNA virus

Orthototiviridae Porifera extended

LC504246

Genome And Source

Length
3,572
Type
ssRNA
GC%
50.8%
Completeness
unknown
Country
Japan
Year
N/A

📋 Data Provenance

🗄️
Source
GenBank / NCBI
🔗
Accession
LC504246
📁
Entry Type
partial_genome
🕒
Last Updated
N/A

Genome Browser

No ORF position data available for this genome.

Curation Status

10
Isolates
2
Hosts
1
Proteins
Sequence

Related Viruses

No related viruses found.

Reference

vAMPirus: A versatile amplicon processing and analysis program for studying viruses.

Veglia AJ, Rivera-Vicéns RE, Grupstra CGB, Howe-Kerr LI, Correa AMS

Molecular ecology resources 2024

PMID: 38775206 DOI: 10.1111/1755-0998.13978

ICTV Mapping

Furovirus avenae
Virgaviridae / Furovirus
auto_matched · high

Reviewed Evidence

Only manual-checked evidence records are displayed. Inferred records (without direct isolate linkage) are shown with a yellow badge.

Virulence / pathogenicity

Molluscan cells in culture: Primary cell cultures and cell lines Detection and Description of a Particular Ostreid Herpesvirus 1 Genotype Associated with Massive Mortality Outbreaks of Pacific oysters, Crassostrea gigas, in France in 2008 Identificat
pathogenicity · medium
Overall, our results show that in a bleaching-resistant coral-holobiont system, dinoRNAVs respond to in situ heat stress and have potentially nuanced, non-lethal health impacts on coral colonies.
pathogenicity · medium
Most of these are secondary metabolites produced by the sponges [3] which may be produced to defend themselves against pathogenic bacteria, algae, fungi and other potential predators; a system they have developed during the process of evolution thr
pathogenicity · medium
Guest (guest) IP: 103.172.183.88 On: Sun, 17 May 2026 04:15:44 Holobiont instability Ecosystem instability Tolerant Cumulative environmental stressors Resilient corals New stable state Mutualistic/ beneficial microbiome Pathogenic state Resilient mi
pathogenicity · medium
Sponge-like proteins represent a novel and powerful weapon that sequesters a variety of second messengers to simultaneously suppress different bacterial immune systems, effectively terminating the process of cell death.
pathogenicity · medium
Comparative Transcriptome Provides a Systematic Perspective on Epstein-Barr Virus-Associated Gastric Carcinoma Cell Lines.
pathogenicity · high
Oncolytic Vaccinia Virus-Mediated Antitumor Effect and Cell Proliferation Were Promoted in PTC by Regulating circRNA_103598/miR-23a-3p/IL-6 Axis.
mortality · high
Thrombospondin-1 inhibits Kaposi's sarcoma (KS) cell and HIV-1 Tat-induced angiogenesis and is poorly expressed in KS lesions.
pathogenicity · high

Temperature

Association of coral algal symbionts with a diverse viral community responsive to heat shock BackgroundStony corals provide the structural foundation of coral reef ecosystems and are termed holobionts given they engage in symbioses, in particular wit
temperature · medium
Isolation of a sulphated polysaccharide from a recently discovered sponge species (Celtodoryx girardae) and determination of its anti-herpetic activity.
temperature · high

Diagnostic And Control Records

No curated diagnostic or control records are available for this virus.

Proteins

🧬

No protein annotations available

Related Literature (385 articles)

State-of-the-Art Strategies for Circular RNA in Cancers: Opportunity and Challenge.
Ding Z, Luo Z, Zhang L, Zhang S, Zhang R, Qiu Z, Huang C.
2026
Spermine and thermospermine synthases emerged multiple times during eukaryote evolution.
Li B, Liang J, Baniasadi HR, Phillips MA, Michael AJ.
2026
International workshop report on "Animal resilience and organismal response to environmental change: insights from basal metazoans", Tutzing (Germany), 22-25 September 2025.
de Luca KL, Ravichandran Y, Dörr M, Voolstra CR.
2026
A Review on Medicinal Chemistry and Biological Activity of Dihydropyrimidinones Against HIV.
Leite DI, Macedo FB, Lima MMC, Brum IS, Oliveira JFM, Costa ACS, Duarte SC, Moon S, Moura SCB, Oliveira AP, Boechat N, Bastos MM
2026
Unveiling the hidden viral biodiversity and potential ecological functions with global coral holobiont virome database.
Wu M, Wen X, Liu S, Ngo HH, Cai Z, Zhou J
2026
Amarilloviruses of Aquatic Animals.
Kibenge F, Kibenge M, Vargas D, Godoy M
2026
Marine-Derived Defenses Against HIV: Emerging Bioactive Molecules from the Seas.
Santos T, Pintão A, Marques CS, Brandão P
2026
NOD-like receptor repertoire in the chromosome-level genome of the demosponge
Koutsouveli V, Torres-Oliva M, Marulanda-Gomez AM, Franke A, Fuß J, Schmitz RA, Hentschel U, Reusch TBH, Pita L
2026
Hydrodynamic dispersion drives viral-cellular contact for gene delivery in porous media.
Srikanth V, Mallory M, Ulmer AJ, Legant WR, Kuznetsov AV, Brudno Y
2026
Onnamides A and B Suppress Hepatitis B Virus Transcription by Inhibiting Viral Promoter Activity.
Hayashi Y, Arizono S, Higa N, Tyas TA, Akahori Y, Maeda K, Toyama M, Mori-Yasumoto K, Yasumoto-Hirose M, Miyakawa K, Tanaka J, Jomori T
2026
Energy production is suppressed by vcircRNA_000048- bom-miR-2753-METTL20 regulatory axis in the BmCPV-infected silkworm, Bombyx mori.
Pang H, Li Y, Zhu M, Tong X, Qiu Q, Li L, Hu X, Gong C, Zhang Y
2026
Circular RNA circPLXNC1 functions as an inhibitor of senescence by regulating autophagy in osteoarthritis.
Zhou H, Ji Z, Sun H, Zhang W, Huang Y, Jin G, Cai H, Huang X, Dai J, Zhao J, Chen H, Fan S, Wu Y, Shen J
2026
Human and pathogen-encoded circular RNAs in viral infections: insights into functions and therapeutic opportunities.
Mueller NL, Dujsikova A, Singh A, Chen YG.
2025
Cloning, expression, and characterization of collagen galactosyltransferases from human, sponge, and sea walnut.
Kim JS, Chen T, Zhang B, Miller TM, Gilliam ME, Guo H.
2025
Marine-Derived Natural Substances with Anticholinesterase Activity.
Dimitrova D, Kehayova G, Dimitrova S, Dragomanova S.
2025
Survival strategies for the microbiome in a vent-dwelling glass sponge from the middle Okinawa Trough.
Li YH, Yang M, Wei TS, Chen HG, Gong L, Wang Y, Gao ZM
2025
A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense.
Chang RB, Toyoda HC, Hobbs SJ, Hadary R, Richmond-Buccola D, Wein T, Osterman I, Burger N, Chouchani ET, Sorek R, Kranzusch PJ
2025
Expression of endogenous Anopheles gambiae microRNAs using an Anopheles gambiae densovirus (AgDNV) intronic expression system.
Johnson RM, Metz HC, Suzuki Y, McLean KJ, Rasgon JL
2025
Synergistic effects of commensals and phage predation in suppressing colonization by pathogenic Vibrio parahaemolyticus.
Chen L, Huang Z, Middelboe M, Deng D, Ma Y
2025
Neuroprotection effect of HSV-1 LAT-derived miR-H2 and miR-H3 associated with Tau and alpha-synuclein downregulation.
Saadatpour F, Fekrirad Z, Mirab SM, Mardani P, Arefian E
2025
Viralization as a microbial approach for enhancing coral reef restoration.
Baer J, Little M, Aquino J, van der Geer A, Sánchez-Quinto A, Ballard A, Lawrence C, Carilli J, Hartmann A, Rohwer F
2025
pH-Dependent Structural Changes in Polyethyleneimine Affect its Gene Transfection Efficiency.
Sharma S, Mishra M, Srivatsav AT, Sharma KP, Kapoor S
2025
Degradable carboxymethyl cellulose/chitosan sponge swabs for sustainable diagnostics.
Liu B, Cheng Z, Xia J, Wang M, Zheng Z, Yang S, Shen Y, Dai D, Wang J, Yu X, Guo C
2025
Sequestering survival: sponge-like proteins in phage evasion of bacterial immune defenses.
Wang L, Zheng R, Zhang L
2025
Hsa_circ_0008085 acts as a miR-146a-5p sponge to suppress influenza a virus replication via modulating of TRAF6.
Yan H, Zhu X, Zhang D, Zhang K, Shi N, Liu X
2025
CircBRWD1 promotes hepatitis B virus replication and hepatocellular carcinoma progression by regulating the miR-513a-5p/TNPO1 axis.
Geng J, Huang F, Liu Q, Wang B, Xiong X, Wang S, Dong Y, Yu Y, Zhao W
2025
Circular RNA Vav3 mediated ALV-J inhibition of autophagy by modulating the gga-miR-375/CIP2A axis and activating AKT.
Chen L, Xu H, Liu R, Yao Z, Xie Q, Zhang X
2025
Hepatitis B Virus X Protein promotes VWF-mediated HCC progression through ST8SIA6-AS1/miR-3150b-3p/ASCL1 axis.
Zhu Y, Zhu Y, Deng Q, Liang X
2025
Identification of RAD51AP1 as a key gene in hepatitis B virus-associated hepatocellular carcinoma.
Wan M, Wang Y, Liu X, Li Y, Deng C, Sun C
2025
PDGFR-α shRNA encoded nanoparticle with epithelial mesenchymal transformation interfering for corneal scarring treatment.
Wang J, Chen Z, Zhang R, Wang Y, Li Y, Xu Z, Lin Q
2025
Coral Disease: Direct and Indirect Agents, Mechanisms of Disease, and Innovations for Increasing Resistance and Resilience.
Vega Thurber RL, Silva D, Speare L, Croquer A, Veglia AJ, Alvarez-Filip L, Zaneveld JR, Muller EM, Correa AMS
2025
Transcriptomic response of Cinachyrella cf. cavernosa sponges to spatial competition.
Deshpande A, Rivera-Vicéns RE, Thakur NL, Wörheide G
2025
Circular RNAs in tumor immunity and immunotherapy.
Zhang W, Xu C, Yang Z, Zhou J, Peng W, Zhang X, Li H, Qu S, Tao K.
2024
Bioinformatics and Experimental Insights Into miR-182, hsa_circ_0070269, and circ-102,166 as Therapeutic Targets for HCV-Associated HCC.
Ishaq Y, Rauff B, Alzahrani B, Ikram A, Javed H, Abdullah I, Mujtaba G.
2024
A 39.8kb flavi-like virus uses a novel strategy for overcoming the RNA virus error threshold
Petrone ME, Grove J, Mifsud JCO, Parry RH, Marzinelli EM, Holmes EC.
2024
DOI
Marine natural products and human immunity: novel biomedical resources for anti-infection of SARS-CoV-2 and related cardiovascular disease.
Hu C.
2024
Improved African Swine Fever Detection for Environmental Samples in the Presence of Organic Contaminants.
Kwon T, Gebhardt JT, Lyoo EL, Gaudreault NN, Trujillo JD, Woodworth JC, Paulk CB, Jones CK, Richt JA
2024
New Sesterterpenes from the Antarctic Sponge
Olsen SSH, Morrow SK, Szabo JL, Teng MN, Tran KC, Amsler CD, McClintock JB, Baker BJ
2024
Characterizing Host microRNA: Virus Interactions of
Mears MC, Bakre A
2024
Phage-induced disturbance of a marine sponge microbiome.
Steiner LX, Schmittmann L, Rahn T, Lachnit T, Jahn MT, Hentschel U
2024
Human Papilloma Virus (HPV) Detection in Oral Rinse vs. Oral Sponge: A Preliminary Accuracy Report in Oral Cancer Patients.
Panzarella V, Buttà M, Buttacavoli F, Capra G, Firenze A, Serra N, Giuliana G, Pizzo G, Campisi G, Mauceri R
2024
Adjuvant Use of the Invariant-Natural-Killer-T-Cell Agonist α-Galactosylceramide Leads to Vaccine-Associated Enhanced Respiratory Disease in Influenza-Vaccinated Pigs.
Artiaga BL, Madden D, Kwon T, McDowell C, Keating C, Balaraman V, de Carvahlo Madrid DM, Touchard L, Henningson J, Meade P, Krammer F, Morozov I, Richt JA, Driver JP
2024
Nanoparticle-Patch System for Localized, Effective, and Sustained miRNA Administration into Infarcted Myocardium to Alleviate Myocardial Ischemia-Reperfusion Injury.
Chen X, Chen H, Zhu L, Zeng M, Wang T, Su C, Vulugundam G, Gokulnath P, Li G, Wang X, Yao J, Li J, Cretoiu D, Chen Z, Bei Y
2024
Fasting-induced miR-7a-5p in AgRP neurons regulates food intake.
Yuan M, Cao Z, Li Q, Liu R, Wang J, Xue W, Lyu Q
2024
The pseudogene GBP1P1 suppresses influenza A virus replication by acting as a protein decoy for DHX9.
Yu X, Tian J, Wang Y, Su N, Luo J, Duan M, Shi N
2024
microRNA-guided immunity against respiratory virus infection in human and mouse lung cells.
Shibamoto A, Kitsu Y, Shibata K, Kaneko Y, Moriizumi H, Takahashi T
2024
PDZ2-conjugated-PLGA nanoparticles are tiny heroes in the battle against SARS-CoV-2.
Giacon N, Lo Cascio E, Pennacchietti V, De Maio F, Santarelli G, Sibilia D, Tiberio F, Sanguinetti M, Lattanzi W, Toto A, Arcovito A
2024
Antiviral Shrimp lncRNA06 Possesses Anti-Tumor Activity by Inducing Apoptosis of Human Gastric Cancer Stem Cells in a Cross-Species Manner.
Khan A, Mohammed A, Zhang X
2024
vAMPirus: A versatile amplicon processing and analysis program for studying viruses.
Veglia AJ, Rivera-Vicéns RE, Grupstra CGB, Howe-Kerr LI, Correa AMS
2024
Suberitolactams A-D and Suberitopyridines A-B: New γ-lactam and Pyridine Alkaloids Isolated from the South China Sea Sponge Pseudospongosorites suberitoides.
Wang Z, Li GQ, Zhang HT
2024

Geographic Distribution

Japan 10 isolates

Taxonomy Information

Family
Orthototiviridae
Host Phylum
Porifera
Genome Type
ssRNA
Discovery Method
metagenomic_survey

ICTV Classification Mapping

Furovirus avenae
Virgaviridae / Furovirus
high

Related Isolates

Accession Length GC Completeness Country Year
LC504241 5,119 48.8 unknown Japan N/A
LC504242 N/A N/A metadata_only Japan N/A
LC504243 N/A N/A metadata_only Japan N/A
LC504244 4,069 51.2 unknown Japan N/A
LC504245 N/A N/A metadata_only Japan N/A
LC504246 3,572 50.8 unknown Japan N/A
LC504247 2,947 50.2 unknown Japan N/A
LC504248 N/A N/A metadata_only Japan N/A
LC504249 2,718 50.4 unknown Japan N/A
LC504250 1,732 52.2 unknown Japan N/A
LC504250 1,732 52.2 unknown Japan N/A

Sequence

Loading sequence...