About AquaVir-KB

Aquatic Invertebrate Virus Knowledge Base

Project Overview

AquaVir-KB is the world's first comprehensive knowledge base dedicated to aquatic invertebrate viruses. The database integrates multi-dimensional data including virus taxonomy, host associations, literature evidence, protein functional annotations, geographic distribution, and phylogenetic analysis. It covers eight host phyla: Arthropoda, Mollusca, Cnidaria, Echinodermata, Porifera, Annelida, Platyhelminthes, and Rotifera, and includes 3,531 virus species and 17,867 isolates.

Formerly CrustaVirus DB v1 (crustacean virus database), expanded in 2026 to cover all aquatic invertebrate viruses.

Data Usage Terms

AquaVir-KB data is licensed under CC BY 4.0. You are free to:

  • Share - copy and redistribute the data
  • Adapt - remix, transform, and build upon the data
  • for any purpose, including commercial use

But must: Attribute - give appropriate credit, provide a link to the license, and indicate if changes were made.

Team

Author, affiliation, and corresponding-author contact details will be finalized upon publication.

Funding

Funding information will be announced upon publication.

Sustainability

AquaVir-KB is committed to long-term operation. The database will be maintained at this URL for at least 5 years following publication (through 2031). Data will be archived with Zenodo (DOI pending assignment) ensuring permanent availability. The source code is available on GitHub.

Data updates are integrated from NCBI GenBank, ICTV, and literature mining on a quarterly basis. All curation workflows are documented and reproducible.

Current Release

Version: schema v9 (2026)

Target virus species: 900 | Evidence records: 353,160 | Viral isolates: 17,867 (全库) | Target isolates: 5,643 | Metagenomic candidates: 8,008 | Proteins: 29,004 | References: 9,069

Host phyla covered: 8 | Countries: 64 | Complete genomes: 390

Zenodo DOI: pending assignment upon publication (permanent data archive)

How to Cite

If you use AquaVir-KB in your research, please cite:

AquaVir-KB Consortium. (2026). AquaVir-KB: a comprehensive knowledge base for aquatic invertebrate viruses. Submitted to Nucleic Acids Research.

A CITATION.cff file is available in the data download area.

Data Sources

NCBI GenBank
Sequences & Isolates
UniProt
Protein Annotations
ICTV
Virus Taxonomy
Europe PMC
Full-text Literature
InterPro
Protein Domains
GBIF / OBIS
Host distribution
AlphaFold / ESMFold
3D Protein Structures
KEGG / STRING
Pathways & Interactions

Technology Stack

Backend: Python FastAPI + SQLite (targeting PostgreSQL migration)

Frontend: Jinja2 + Tailwind CSS + HTMX + ECharts

Data Pipeline: ~60 Python scripts (NCBI / UniProt / InterPro / KEGG / EPMC / SRA)

Deployment: Docker Compose + Nginx + HTTPS

Versioning: Zenodo DOI