Macrobrachium rosenbergii nodavirus

Nodaviridae Arthropoda extended

DQ459206.1

罗氏沼虾诺达病毒

Genome And Source

Length
592
Type
ssRNA(+)
GC%
43.8%
Completeness
partial_sequence
Country
Taiwan
Year
N/A

📋 Data Provenance

🗄️
Source
GenBank / NCBI
🔗
Accession
DQ459206.1
📁
Entry Type
complete_genome
🕒
Last Updated
N/A

Genome Browser

No ORF position data available for this genome.

Curation Status

100
Isolates
3
Hosts
1
Proteins
Sequence

Related Viruses

No related viruses found.

Outbreak Events

None

Associated with WTD outbreaks in prawn hatcheries; mortality mainly in larval stages with XSV co-infection

Reference

Chimeric virus-like particles carrying the CLEC17A carbohydrate-recognition domain significantly reduce Macrobrachium rosenbergii nodavirus infection in Sf9 cells

Chantunmapitak R; Boonkua S; Thongsum O; Breiman A; Weerachatyanukul W; Asuvapongpatana S; Watthammawut A; Somrit M

Scientific reports 2025

PMID: 41361223 DOI: 10.1038/s41598-025-27357-3

ICTV Mapping

No reviewed species-level mapping is available. Family-level ICTV references:

  • Alphanodavirus boolarraense (Alphanodavirus)
  • Alphanodavirus flockense (Alphanodavirus)
  • Alphanodavirus heteronychi (Alphanodavirus)
  • Alphanodavirus nodamuraense (Alphanodavirus)
  • Alphanodavirus pariacotoense (Alphanodavirus)

Reviewed Evidence

Only manual-checked evidence records are displayed. Inferred records (without direct isolate linkage) are shown with a yellow badge.

Virulence / pathogenicity

mortality_rate: 95
mortality_rate: 95
mortality · medium
Auto-extracted: mortality in 'Genetic Reassortment between Endemic and Introduced'
mortality · medium
Auto-extracted: pathogenicity in 'In vitro replication of Macrobrachium rosenbergii nodavirus and extra small virus in C6/36 mosquito cell line.'
, anorexia and opaqueness of abdominal muscle and 100% mortality was observed at 6 days post-infection.
pathogenicity · medium
Auto-extracted: mortality in 'In vitro replication of Macrobrachium rosenbergii nodavirus and extra small virus in C6/36 mosquito cell line.'
, anorexia and opaqueness of abdominal muscle and 100% mortality was observed at 6 days post-infection.
mortality · medium
Auto-extracted: mortality in 'Experimental transmission and tissue tropism of Macrobrachium rosenbergii nodavirus (MrNV) and its associated extra smal'
tally transmitted to healthy animals, they caused 100% mortality in post-larvae but failed to cause mortality in a
mortality · medium
Auto-extracted: pathogenicity in 'Oral vaccination of Macrobrachium rosenbergii with baculovirus-expressed M. rosenbergii nodavirus (MrNV) capsid protein'
rosenbergii larvae succumbed to death and had 90% mortality, whereas the r-MrNV protein treated groups exhibi
pathogenicity · medium
Auto-extracted: mortality in 'Oral vaccination of Macrobrachium rosenbergii with baculovirus-expressed M. rosenbergii nodavirus (MrNV) capsid protein'
rosenbergii larvae succumbed to death and had 90% mortality, whereas the r-MrNV protein treated groups exhibi
mortality · medium
Auto-extracted: mortality in 'White Tail Disease of Freshwater Prawn, Macrobrachium rosenbergii.'
In experimental infection, these viruses caused 100 % mortality in post-larvae but failed to cause mortality in a
mortality · medium
Auto-extracted: mortality in 'Recombinant viral proteins delivered orally through inactivated bacterial cells induce protection in Macrobrachium rosen'
rols of groups I, II and III showed 100%, 95% and 95% mortality, respectively.
mortality · medium
Auto-extracted: mortality in 'Truncation-Enhanced Aptamer Binding Affinity and Its Potential as a Sensor for Macrobrachium rosenbergii Nodavirus Detec'
ii nodavirus (MrNV) infection, resulting in up to 100% mortality in larvae and post-larvae stages, severely impact
mortality · medium

Temperature

Expression and characterization of hepatitis B virus surface antigen polypeptides in insect cells with a baculovirus expression system Purification and characterization of Nipah virus nucleocapsid protein produced in insect cells Production and biome
temperature · medium
Fulltext: degree, °C
temperature · medium
Fulltext: thermal
temperature · medium
Fulltext: heat shock, degree, °C
temperature · medium
Fulltext: °C
temperature · medium
Fulltext: degree, °C
temperature · medium
Fulltext: thermal
Macrobrachium rosenbergii nodavirus along with a satellite virus, extra small virus (XSV) causes white tail disease (WTD) in the giant freshwater prawn M.
temperature · medium
Fulltext: °C
temperature · medium
Fulltext: thermal, °C
temperature · medium
Macrobrachium rosenbergii nodavirus temperature profile
Optimal replication in larval rearing temps (26-30°C); disease expression requires co-infection with XSV; temperature effect on co-infection dynamics unclear
temperature · high

Diagnostic And Control Records

Diagnostic methods

Truncation-Enhanced Aptamer Binding Affinity and Its Potential as a Sensor for Macrobrachium rosenbergii Nodavirus Detec
Immunoassay · target not specified
medium

Proteins

🧬

No protein annotations available

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Florea A, Wade N, Salisbury SJ, Furniss J, Fraslin C, Chapuis A, Sullivan K, Stewart R, Robledo D, Bean TP
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Insect SVWC Proteins: A Diverse Cytokine-like Family Orchestrating Multilayered Antiviral and Antibacterial Immunity.
Chen Y, Xu G, Wang J, Zhang C, Abubakar AY, Xia H
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Amarilloviruses of Aquatic Animals.
Kibenge F, Kibenge M, Vargas D, Godoy M
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Chamonara K, Masum MHU, Uddin MS, Siddiqua A, Sultana S, Islam S
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Dietary inclusion of Allium cepa and Allium sativum extract improves growth performance, haematological and immunological indices, body composition and disease resistance of prawn (Macrobrachium rosenbergii) against Vibrio parahaemolyticus infection.
Adhikary U, Ahmmed SS, Sadia HT, Sarkar R, Nasrin F, Ghosh AK
2026
Virus-like particles of Macrobrachium rosenbergii nodavirus displaying M2e of influenza A viruses protect White Leghorn chickens against heterologous H9N2 and H5N2 challenges.
Thian BYZ, Fatimah MNN, Omar AR, Hussin H, Ong HK, Wong CL, Mariatulqabtiah AR, Ho KL, Tan WS
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2026
DOI
Submersion Treatment of Chimeric MrN-VLPs Encapsulating Therapeutic Double-Stranded RNA Effectively Rescues Prawn Viral Infection.
Thongsum O, Boonkua S, Jaranathummakul S, Somrit M, Chotwiwatthanakun C, Asuvapongpatana S, Jariyapong P, Weerachatyanukul W.
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Changes in Intestinal Microbial Community of the Black Tiger Shrimp
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WSSV-induced reversal of the malate-aspartate shuttle facilitates viral replication in shrimp hemocytes.
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The Regulatory Effect and Molecular Mechanism of the Anti-Lipopolysaccharide Factor-like Gene on the Resistance of Shrimp (
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2025
Infection with infectious precocious virus (IPV) suppresses infection with decapod iridescent virus 1 (DIV1) in Macrobrachium rosenbergii.
Lou H, Wang G, Li X, Zhou C, Guo X, Wang L, Tang Q, Yang G, Dong X, Huang J.
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Lou H, Li X, Wang G, Zhang K, Wang K, Tang Q, Yang G, Jia P, Xiong J, Huang J, Dong X.
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Unknown (pending verification)
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Truncation-Enhanced Aptamer Binding Affinity and Its Potential as a Sensor for Macrobrachium rosenbergii Nodavirus Detec
Unknown (pending verification)
2025
Chimeric virus-like particles carrying the CLEC17A carbohydrate-recognition domain significantly reduce Macrobrachium rosenbergii nodavirus infection in Sf9 cells
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Wang Y, Dai L, Liang Z, Hu N, Hou D, Zhou Y, Sun C
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Comparative transcriptomic and molecular biology analyses to explore potential immune responses to
Chen D, Xin Y, Teng J, Zhao X, Lu J, Li Y, Wang H
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Boonkua S, Thongsum O, Soongnart P, Chantunmapitak R, Jaranathummakul S, Srisanga K, Asuvapongpatana S, Wongtrakoongate P, Weerachatyanukul W, Watthammawut A, Somrit M
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Pudgerd A, Saedan S, Santimanawong W, Weerachatyanukul W, Jariyapong P, Chaijarasphong T, Jongsomchai K, Sritunyalucksana K, Vanichviriyakit R, Chotwiwatthanakun C
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Zheng Y, Guo G, Lv Y, Gao Q, Zhou D, Zhang L, Tu G, Weng S, Li C, He J, Wang M
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Differential expression of microRNAs in giant freshwater prawn (Macrobrachium rosenbergii) during the infection of Vibrio parahaemolyticus.
Li Y, Xu Q, Liu H, Dai X
2024
Comparative transcriptome analysis reveals the different responding mechanisms of ovary and hepatopancreas following polyI:C challenge in Macrobrachium nipponense.
Wan H, Yu L, Cui X, Guo S, Mu S, Kang X
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Du J, Tang Y, Chu J, Yang Q, Qian X, Wan Y, Lu Y, Zhang L, Wang W
2024
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Muikham I, Thongsum O, Jaranathummakul S, Wathammawut A, Chotwiwatthanakun C, Jariyapong P, Weerachatyanukul W
2024
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Moh JHZ, Okomoda VT, Mohamad N, Waiho K, Noorbaiduri S, Sung YY, Manan H, Fazhan H, Ma H, Abualreesh MH, Ikhwanuddin M
2024
The identification of a serpin with immune defense role in oriental river prawn Macrobrachium nipponense.
Jiang H, Li H, Liu X, Zhang S, Li X, Wang L, Zhang M, Yu M, Li X, Qiao Z
2024
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Geographic Distribution

Canada 17 isolates
China 15 isolates
Australia 14 isolates
India 11 isolates
Thailand 8 isolates
Taiwan 8 isolates
South Korea 3 isolates
Malaysia 2 isolates

Taxonomy Information

Family
Nodaviridae
Host Phylum
Arthropoda
Genome Type
ssRNA(+)
Discovery Method
metagenomic_with_host_evidence

Related Isolates

Accession Length GC Completeness Country Year
AM114036.1 384 43.2 partial_sequence Canada 2023
AY222839.1 3,202 44.2 complete_genome Canada 2023
AY222840.1 1,175 40.3 complete_genome Canada 2023
AY231436.2 3,199 44.4 partial_sequence China 2001
AY231437.2 1,175 39.8 gene_fragment China 2001
AY313773.1 630 46.5 partial_sequence N/A 2005
AY655724.2 872 42.9 mRNA China 2001
DQ011290.1 622 42.9 partial_sequence India 2016
DQ146969.1 859 43.2 partial_sequence India 2008
DQ189990.1 606 39.4 mRNA Thailand 1999
DQ459203.1 592 43.9 partial_sequence Taiwan 2000
DQ459204.1 592 43.9 partial_sequence Taiwan 2000
DQ459205.1 592 43.8 partial_sequence Taiwan 2000
DQ459206.1 592 43.8 partial_sequence Taiwan 2000
DQ459207.1 592 43.8 partial_sequence Taiwan 2000
DQ459208.1 592 43.9 partial_sequence Taiwan 2000
DQ521574.1 856 43.9 partial_sequence Taiwan 2000
DQ521575.1 1,121 40.7 genome_segment Taiwan 2000
EU150126.1 1,172 40.4 gene_fragment Thailand 2007
EU150127.1 1,170 40.4 gene_fragment Thailand 2007
EU150128.1 1,171 40.5 gene_fragment Thailand 2007
EU150129.1 1,170 40.9 gene_fragment Thailand 2007
FJ360617.1 302 39.4 partial_sequence Thailand 2007
FJ360618.1 302 39.7 partial_sequence Thailand 2007
FJ379530.1 682 39.4 partial_sequence Australia 2007
FJ379531.1 861 42.6 partial_sequence Australia 2007
FJ751225.1 1,175 39.8 complete_genome China 2006
FJ751226.1 3,126 44.2 partial_sequence China 2006
GU300102.1 1,116 41.0 gene_fragment India 2011
GU300103.1 402 50.2 gene_fragment India 2011
GU476556.1 658 38.5 partial_sequence Canada 2023
GU476557.1 477 39.4 partial_sequence Canada 2023
GU476558.1 657 38.8 partial_sequence Canada 2023
GU476559.1 472 37.9 partial_sequence Canada 2023
GU476560.1 336 38.7 partial_sequence Canada 2023
GU476561.1 658 38.5 partial_sequence Canada 2023
GU476562.1 658 38.5 partial_sequence Canada 2023
GU476563.1 658 38.5 partial_sequence Canada 2023
GU476564.1 626 36.7 partial_sequence Canada 2023
GU476565.1 622 37.3 partial_sequence Canada 2023
GU476566.1 637 36.4 partial_sequence Canada 2023
GU476567.1 658 38.6 partial_sequence Canada 2023
HM565741.1 1,072 41.2 partial_sequence India 2010
HQ287005.1 681 39.4 partial_sequence China 2001
HQ637179.1 1,121 40.9 gene_fragment India 2008
JN187416.1 3,199 44.5 gene_fragment Malaysia 2011
JN571287.1 423 41.6 partial_sequence China 2001
JN571288.1 205 44.4 partial_sequence China 2001
JN619369.1 3,203 44.5 complete_genome Australia 2004
JN619370.1 1,173 39.6 complete_genome Australia 2004
JQ418295.1 3,126 44.4 partial_sequence India 2008
JQ418296.1 1,116 40.7 gene_fragment India 2008
JQ418297.1 402 50.2 gene_fragment India 2008
JQ418298.1 1,175 40.2 genome_segment India 2008
JQ965671.1 1,121 40.4 gene_fragment China 2003
JQ965672.1 1,121 40.3 gene_fragment China 2011
JQ965673.1 1,121 40.8 gene_fragment China 2001
JQ965674.1 1,121 41.2 gene_fragment China 2011
JQ965675.1 1,121 40.4 gene_fragment China 2011
JQ965676.1 1,121 41.2 gene_fragment China 2011
KF824532.1 1,112 40.9 partial_sequence Indonesia 2011
KF824533.1 1,312 46.0 partial_sequence Indonesia 2011
KJ000009.1 1,125 39.7 genome_segment Malaysia 2010
KP941742.1 1,138 40.3 gene_fragment China 2001
KY496616.1 1,175 40.6 mRNA Thailand 2015
MG063722.1 205 43.4 mRNA India 2017
NC_005094 3,202 44.2 unknown N/A N/A
NC_005094.1 3,202 44.2 complete_genome Canada 2023
NC_005095 1,175 40.3 unknown N/A N/A
NC_005095.1 1,175 40.3 complete_genome Canada 2023
OP434475.1 205 43.9 partial_sequence South Korea 2021
OP434476.1 205 43.9 partial_sequence South Korea 2021
OP434477.1 205 43.9 partial_sequence South Korea 2021
OP508292.1 3,117 44.7 gene_fragment Australia 2020
OP508293.1 3,117 44.7 gene_fragment Australia 2020
OP508294.1 3,117 44.6 gene_fragment Australia 2020
OP508295.1 3,117 44.1 gene_fragment Australia 2020
OP508296.1 3,117 44.1 gene_fragment Australia 2020
OP508297.1 1,116 40.5 gene_fragment Australia 2020
OP508298.1 1,116 40.4 gene_fragment Australia 2020
OP508299.1 1,116 40.2 gene_fragment Australia 2020
OP508300.1 1,116 40.3 gene_fragment Australia 2020
OP508301.1 1,116 40.4 gene_fragment Australia 2020
PX942099.1 5,295 37.0 unknown N/A N/A
PX942102.1 5,435 35.0 unknown N/A N/A
PX942105.1 5,703 38.9 unknown N/A N/A
PX942111.1 3,391 37.3 unknown N/A N/A
PX942113.1 5,072 34.9 unknown N/A N/A
PX942134.1 3,395 54.5 unknown N/A N/A
PX942135.1 3,401 54.7 unknown N/A N/A
PX942143.1 3,365 54.1 unknown N/A N/A
PX942152.1 3,334 41.9 unknown N/A N/A
PX942153.1 3,656 40.0 unknown N/A N/A
PX942158.1 3,452 54.8 unknown N/A N/A
PX942167.1 4,560 51.3 unknown N/A N/A
PX942190.1 3,331 55.1 unknown N/A N/A
PX942191.1 3,412 54.0 unknown N/A N/A
PX942207.1 3,366 55.0 unknown N/A N/A
PX942217.1 3,351 53.8 unknown N/A N/A
PZ065988.1 2,726 42.3 unknown N/A N/A

Sequence

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